Why I like ISC...

"ISC has evolved over 20 years to the only European key event addressing all aspects of High Performance Computing. It is strongly recommended for executives from research, academia and industry who want mangement-style updates in a very professional and compact but also entertaining way."
Dr. Frank Baetke, Global HPC-Technology Program Manager, Hewlett-Packard

Why I like ISC...

"ISC has evolved over 20 years to the only European key event addressing all aspects of High Performance Computing. It is strongly recommended for executives from research, academia and industry who want mangement-style updates in a very professional and compact but also entertaining way."
Dr. Frank Baetke, Global HPC-Technology Program Manager, Hewlett-Packard

Why I like ISC...

"HPC practitioners in academia, government and industry are harnessing advanced computing to push the envelope of science and technology. Every year, ISC brings this dedicated community together to share the insights, celebrate the accomplishments and map out the future."
Kyril Faenov, General Manager HPC, Microsoft Corporation

Why I like ISC...

"Europe is not the continent to produce the majority of supercomputers - its contribution focusses on super algorithms and applications. ISC is the place where both fields merge in Europe and consequently a must for the annual agenda."
Prof. Dr. Frank Behrendt, Berlin Institute of Technology, Department of Energy Engineering

Why I like ISC...

"As a national supercomputing center, we need to update ourselves with recent HPC technology and applications. ISC is the best place for this purpose because every year ISC invites excellent speakers and combines exciting topics and exhibition. It is also reasonable size conference, I love it."
Dr. Sik Lee, Team Leader, KISTI Supercomputing Center, Korea

Why I like ISC...

"ISC provides an ideal mix of focused technical presentations, exhibitor demonstrations, and time to mingle with other participants. Attendance is small enough to have a discussion and diverse enough to get a variety of viewpoints, especially those of the key international HPC players."
Dona Crawford, Associate Director Computation, Lawrence Livermore National Laboratory

Why I like ISC...

"I have been attending ISC since 1987, I remember that being an exciting time for high-performance computing as it is today. The ISC conference has, since its beginning, been a venue for a stimulating program with the leading experts in the HPC area."
Dr. Jack Dongarra, Distinguished Professor, University of Tennessee

Why I like ISC...

"ISC offers a platform on which users from science, industry as well as vendors and industry observers have a chance to meet and discuss, unlike almost any other place in the world. As an industry representative, I have gained tremendous value from attending the event."
Dave Turek, Vice President, Deep Computing, IBM

Why I like ISC...

"I often find that I learn more at ISC compared to IEEE/ACM SCxx. The combination of more concentrated technical focus, combined with the great hospitality of the organizers, creates a unique experience. You've got to be there to really understand the draw of the event."
Dr. Horst Simon, Associate Laboratory Director, Lawrence Berkeley National Laboratory

Why I like ISC...

"I like ISC because this is where HPC Europe meets the world. ISC is the place to discuss cross-Atlantic issues and keep in touch with Asia. I like its unique atmosphere of work and recreation. ISC is where scientists meet to enjoy discussions and build communities."
Prof. Dr.-Ing. Michael Resch, Director, HLRS Stuttgart

Why I like ISC...

"ISC is the most important HPC event in Europe. ISC combines scientific and technical issues in an unique way, and makes this event most productive and enjoyable."
Dr. Andreas Adelmann, Staff Scientist, Paul Scherrer Institute (PSI)

Why I like ISC...

"I attended ISC'07 for the first time and it was a good decision. As a developing center, CHPC benefited greatly from the Hot-Seat session, where technology manufacturers were grilled. This session makes it easy for new entrants into HPC to understand the dynamics and technicalities on deciding on technologies to implement."
Dr. Happy Sithole, Director, CHPC, South Africa

Why I like ISC...

"For Cray, the ISC conference in June is a great event. ISC is a 'must attend' event, with an atmosphere more intimate and conducive to useful dialogues than larger HPC conferences in the U.S. ISC combines excellent organization, attractive suroundings, an exciting agenda and an uncompromised commitment to HPC."
Dr. Ulla Thiel, Vice President Europe, Cray

Why I like ISC...

"ISC has always been my favorite. The continuously highest international quality, the great selection of world-class speakers, the ideal mix of high-level research, business and industry talks, and Hans Meuer's unique gift to maintain a familiar atmosphere make this a unique conference and a 'must participate'!"
Prof. Dr. Wolfgang Gentzsch, EU Project DEISA

Why I like ISC...

"ISC has established itself as the key European HPC event while maintaining a technically focused atmosphere. We look forward to Intel's continued association with ISC for many years to come."
Stephan Gillich, HPC Marketing Manager EMEA, Intel

Abstract

A BioMoby-Based Workflow for Gene Detection Using Sequence Homology

Prof. Dr. Josep Ll. Gelpí
Leader of National Institute of Bioinformatics Node
Barcelona Supercomputing Center (BSC), Spain


A BioMoby workflow to help gene detection from genomic DNA sequence based on sequence comparison is presented. Input data is a reference protein sequence and the target a genomic sequence. Workflow is based in the genomic analysis genewise. Genomic sequences are prescanned with a TBLASTN search usign the input protein sequence as query, and filtered through blast2gene to define candidate genomic regions. This approach have been proved successful as it is able to detect not only functional genes but also non-functional copies or fragments that are usually overlooked in public gene databases. It also has proven superior to pure HMM based gene prediction approaches. The use of an automated BioMoby based approach, instead of a “manual” analysis, significantly reduces the effort required to apply the workflow to new genomes in a systematic way. Moreover, the modular nature of the individual BioMoby services enables fine-grained reusing of each service in related projects. Additionally, a model for data persistence, not available so far within the BioMoby protocol, is presented. The model would allow extending the standard towards the use of large amounts of data, currently one of the most relevant issues in this kind of technology.



Sponsors

The ongoing success of the International Supercomputer Conference is due in large part to our sponsors. We are pleased to highlight that Intel is the premier sponsor for ISC'08. The list of co-sponsors includes many of the major players in the HPC world. » more

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